Phospho-ULK1 (S556) antibody
Product Specifications
Background
ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase (FAK) family interacting protein of 200 kDa (FIP 200) (PMID:21460634) . ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC (PMID:23573318) .
Synonyms
Serine/threonine-protein kinase ULK1|Autophagy-related protein 1 homolog (ATG1, hATG1) |Unc-51-like kinase 1|ULK1|KIAA0722
Gene ID
8408
UniProt
O75385
Host
Rabbit
Reactivity
Human
Immunogen
Peptide
Target
Phospho-ULK1 (S556) ULK1
Clonality
Polyclonal
Isotype
IgG
Field of Research
Cardiovascular, Metabolism, Developmental biology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140-150 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
WB
Immunogen Sequence
Peptide
Curated Selection
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