Phospho-Smad3 (S423/S425) antibody
Product Specifications
Background
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
Synonyms
Mothers against decapentaplegic homolog 3 (MAD homolog 3, Mad3, Mothers against DPP homolog 3, hMAD-3) |JV15-2|SMAD family member 3 (SMAD 3, Smad3, hSMAD3) |SMAD3|MADH3
Gene ID
4088
UniProt
P84022
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SMAD family member 3
Target
Phospho-Smad3 (S423/S425)
Clonality
Polyclonal
Isotype
IgG
Field of Research
Epigenetics, Signal Transduction, Metabolism, Cardiovascular, Cancer, Developmental biology, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:1000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
