CD63 antibody

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

CD63 antigen|Granulophysin|Lysosomal-associated membrane protein 3 (LAMP-3) |Lysosome integral membrane protein 1 (Limp1) |Melanoma-associated antigen ME491|OMA81H|Ocular melanoma-associated antigen|Tetraspanin-30 (Tspan-30) |CD63|MLA1|TSPAN30