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PE-Cy7 Anti-Human CD62L Antibody (DREG56)

Product Specifications

Background

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

Synonyms

L-selectin|CD62 antigen-like family member L|Leukocyte adhesion molecule 1 (LAM-1) |Leukocyte surface antigen Leu-8|Leukocyte-endothelial cell adhesion molecule 1 (LECAM1) |Lymph node homing receptor|TQ1|gp90-MEL|SELL|LNHR|LYAM1

Gene ID

6402

UniProt

P14151

Host

Mouse

Reactivity

Human

Immunogen

L-selectin

Target

Human CD62L

Clonality

Monoclonal

Isotype

IgG1 kappa

Conjugation

PE-Cy7

Dilution

Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) . Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Form

Liquid

Storage Conditions

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

DREG56

Tested Applications

FC

Conjugation Information

PE-Cy7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter) .

Available Sizes

Frequently Asked Questions

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