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FITC Anti-Human HLA-A2, B7 (BB7.6)

Product Specifications

Background

HLA-A2 is most common in Northern Asia and North America populations. MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells, playing an important role in cell-mediated immune responses and tumor surveillance.HLA-B belongs to the HLA class I heavy chain paralogues. HLA-B7 is a serotype of HLA-B and one of the common HLA types. MHC class I heavy chains associate with β2-microglobulin and are expressed on nearly all nucleated cells. MHC class I molecules are involved in the presentation of of antigens to CD8+ T cells and thereby play an important role in cell-mediated immune responses and immune surveillance.

Synonyms

HLA class I histocompatibility antigen, A alpha chain|Human leukocyte antigen A (HLA-A) |HLA-A|HLAA|HLA-A2|HLA-B7

Gene ID

3105

UniProt

P04439

Host

Mouse

Reactivity

Human

Target

Human HLA-A2, B7

Clonality

Monoclonal

Isotype

IgG1 kappa

Conjugation

FITC

Dilution

Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) . Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Form

Liquid

Storage Conditions

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

BB7.6

Tested Applications

FC

Conjugation Information

FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter) .

Available Sizes

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