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8-epi-Helenalin

Product Specifications

UNSPSC Description

8-epi-Helenalin is a semitterpene lactone with anti-tumor activity that can be isolated from Inula britannicaL. var. chinensis (Rupr.) Reg. and the ED50 values of 8-epi-Helenalin for HL-60, A549, MCF7, HCT-15, SK-OV-3 and Malme-3M are 12.2 μM, 53.8 μM, 9.1 μM, 8.7 μM, 18.7 μM and 8.3 μM, respectively. 8-epi-Helenalin can be used for anti-tumor studies[1].

Target Antigen

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/8-epi-helenalin.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@](C=CC2=O)([H])[C@@H](C[C@@]3([H])[C@](C(C(O3)=O)=C)([H])[C@@H]1O)C

Molecular Weight

262.30

References & Citations

[1]Park EJ, et al. Cytotoxic sesquiterpene lactones from Inula britannica. Planta Med. 1998 Dec;64(8):752-4.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N12589/8-epi-Helenalin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N12589/

Clinical Information

No Development Reported

CAS Number

97643-91-9

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