8-epi-Helenalin
8-epi-Helenalin is a semitterpene lactone with anti-tumor activity that can be isolated from Inula britannicaL. var. chinensis (Rupr.) Reg. and the ED50 values of 8-epi-Helenalin for HL-60, A549, MCF7, HCT-15, SK-OV-3 and Malme-3M are 12.2 μM, 53.8 μM, 9.1 μM, 8.7 μM, 18.7 μM and 8.3 μM, respectively. 8-epi-Helenalin can be used for anti-tumor studies[1].
Product Specifications
CAS Number
[97643-91-9]
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-epi-helenalin.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](C=CC2=O)([H])[C@@H](C[C@@]3([H])[C@](C(C(O3)=O)=C)([H])[C@@H]1O)C
Molecular Formula
C15H18O4
Molecular Weight
262.30
References & Citations
[1]Park EJ, et al. Cytotoxic sesquiterpene lactones from Inula britannica. Planta Med. 1998 Dec;64 (8) :752-4.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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