Defensin NP-3A
Defensin NP-3A (NP-3A; Corticostatin 1) is a human granulocyte peptide, with anti-ACTH activity. Defensins are antimicrobial peptides with and cytotoxic activity[1][2].
Product Specifications
CAS Number
134090-73-6
Product Name Alternative
NP-3A; Corticostatin 1, rabbit
UNSPSC
12352209
Target
Bacterial; Melanocortin Receptor
Type
Peptides
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/defensin-np-3a.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)NC1=O)C(N[C@@H](C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(NCC(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](C(C)C)C(N[C@H]3CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC4=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CSSC[C@@H]1NC3=O)C(N6[C@@H](CCC6)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC7=CC=CC=C7)C(N[C@@H](CO)C(NCC(N[C@H]4CC8=CC=C(C=C8)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN
Molecular Formula
C163H259N63O44S6
Molecular Weight
3997.59
References & Citations
[1]Singh A, et al. Structure of a novel human granulocyte peptide with anti-ACTH activity. Biochem Biophys Res Commun. 1988 Aug 30;155 (1) :524-9. |[2]Lehrer RI, et al. Defensins: antimicrobial and cytotoxic peptides of mammalian cells. Annu Rev Immunol. 1993;11:105-28.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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