Olomorasib
Olomorasib is a potent inhibitor of KRAS G12C. Olomorasib significantly inhibits tumor growth (extracted from patent WO2021118877A1) [1].
Product Specifications
CAS Number
2771246-13-8
Product Name Alternative
KRAS G12C inhibitor 19
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-19.html
Purity
98.48
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC1=CC=[C@]([C@]2=C(F)C=C(C(N3[C@@](CN(CC3)C(C=C)=O)([H])CCO4)=O)C4=C2Cl)C5=C1SC(N)=C5C#N
Molecular Formula
C25H19ClF2N4O3S
Molecular Weight
528.96
Precautions
H302, H315, H319
References & Citations
[1]Serge Louis Boulet, et al. Kras g12c inhibitors. Patent WO2021118877A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
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