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Olomorasib

Olomorasib is a potent inhibitor of KRAS G12C. Olomorasib significantly inhibits tumor growth (extracted from patent WO2021118877A1) [1].

Product Specifications

CAS Number

2771246-13-8

Product Name Alternative

KRAS G12C inhibitor 19

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kras-g12c-inhibitor-19.html

Purity

98.48

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC1=CC=[C@]([C@]2=C(F)C=C(C(N3[C@@](CN(CC3)C(C=C)=O)([H])CCO4)=O)C4=C2Cl)C5=C1SC(N)=C5C#N

Molecular Formula

C25H19ClF2N4O3S

Molecular Weight

528.96

Precautions

H302, H315, H319

References & Citations

[1]Serge Louis Boulet, et al. Kras g12c inhibitors. Patent WO2021118877A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Available Sizes

Frequently Asked Questions

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