CSF1R-IN-24

CSF1R-IN-24 (Example 134) is an orally active CSF1R inhibitor. CSF1R-IN-24 significantly inhibits the survival of human ipSC-derived microglia (hiPSC-MG) [1].

Product Specifications

CAS Number

[3024322-57-1]

UNSPSC

12352005

Target

C-Fms

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/csf1r-in-24.html

Purity

98.10

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC1=CC(CC2=CC=NC3=C2N=CC(C4=NN(C)C=C4)=C3)=CN=C1OCC5=NC=C(C=C5)OC

Molecular Formula

C26H24N6O3

Molecular Weight

468.51

References & Citations

[1]Hao Wang, et al. Csf-1r inhibitors and uses thereof . WO2023241608A1. 2023.12.21.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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