[1,1′:4′,1′′-Terphenyl]-3,4′′,5-triol

[1,1′:4′,1′′-Terphenyl]-3,4��′,5-triol (compound 13g) is a terphenyl derivative that blocks the cell cycle in the G0-G1 phase and induces differentiation in leukemia cells. [1,1′:4′,1′′-Terphenyl]-3,4′′,5-triol shows a potent apoptotic effect[1].

Product Specifications

CAS Number

[890854-82-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/1-1-4-1-terphenyl-3-4-5-triol.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=C(C2=CC=C(C3=CC(O)=CC(O)=C3)C=C2)C=C1

Molecular Formula

C18H14O3

Molecular Weight

278.30

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Marinella Roberti, et al. Identification of a terphenyl derivative that blocks the cell cycle in the G0-G1 phase and induces differentiation in leukemia cells. J Med Chem. 2006 May 18;49 (10) :3012-8.