KD 5170
KD 5170 is a pan inhibitor of histone deacetylases (HDACs) and exhibits broad spectrum antitumor activity in vitro and in vivo[1].
Product Specifications
CAS Number
[940943-37-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kd-5170.html
Purity
98.13
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(NC1=CC=C(C(CSC(C)=O)=O)C=N1)(C2=CC=C(OCCCN(C)C)C=C2)=O
Molecular Formula
C20H25N3O5S2
Molecular Weight
451.56
Precautions
H302, H315, H319, H335
References & Citations
[1]Hassig CA, et al. KD5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo. Mol Cancer Ther. 2008 May;7 (5) :1054-65.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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