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KD 5170

KD 5170 is a pan inhibitor of histone deacetylases (HDACs) and exhibits broad spectrum antitumor activity in vitro and in vivo[1].

Product Specifications

CAS Number

[940943-37-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kd-5170.html

Purity

98.13

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(NC1=CC=C(C(CSC(C)=O)=O)C=N1)(C2=CC=C(OCCCN(C)C)C=C2)=O

Molecular Formula

C20H25N3O5S2

Molecular Weight

451.56

Precautions

H302, H315, H319, H335

References & Citations

[1]Hassig CA, et al. KD5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo. Mol Cancer Ther. 2008 May;7 (5) :1054-65.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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