Azamulin
Azamulin is an irreversible, highly selective inhibitior of human CYP3Aa. Azamulin has CYP3A inhibition activity with IC50 values range from 0.03-0.24 μM. Azamulin can be used for the research of metabolism and antiinfection[1].
Product Specifications
CAS Number
76530-44-4
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/azamulin.html
Purity
97.94
Solubility
DMSO : ≥ 100 mg/mL
Smiles
C[C@@H]1[C@]23[C@](C(CC3)=O)([H])[C@]([C@@H](C[C@](C)([C@H]1O)CC)OC(CSC4=NN=C(N)N4)=O)([C@@H](CC2)C)C
Molecular Formula
C24H38N4O4S
Molecular Weight
478.65
Precautions
H315, H319, H335
References & Citations
[1]David M Stresser, et al. Highly selective inhibition of human CYP3Aa in vitro by azamulin and evidence that inhibition is irreversible. Drug Metab Dispos. 2004 Jan;32 (1) :105-12.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP3
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LY400509 100 µg
Liver Carboxylesterase 1 (CES1) (NM_001266) Human Over-expression Lysate
Sign In for Pricing
View Details 
