Azamulin
Azamulin is an irreversible, highly selective inhibitior of human CYP3Aa. Azamulin has CYP3A inhibition activity with IC50 values range from 0.03-0.24 μM. Azamulin can be used for the research of metabolism and antiinfection[1].
Product Specifications
CAS Number
76530-44-4
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/azamulin.html
Purity
97.94
Solubility
DMSO : ≥ 100 mg/mL
Smiles
C[C@@H]1[C@]23[C@](C(CC3)=O)([H])[C@]([C@@H](C[C@](C)([C@H]1O)CC)OC(CSC4=NN=C(N)N4)=O)([C@@H](CC2)C)C
Molecular Formula
C24H38N4O4S
Molecular Weight
478.65
Precautions
H315, H319, H335
References & Citations
[1]David M Stresser, et al. Highly selective inhibition of human CYP3Aa in vitro by azamulin and evidence that inhibition is irreversible. Drug Metab Dispos. 2004 Jan;32 (1) :105-12.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP3
Available Sizes
Frequently Asked Questions
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