Gomisin M2

Gomisin M2 ((+) -Gomisin M2) is a lignan isolated from the fruits of Schisandra rubriflora with anti-HIV activity (EC50 of 2.4 μM) . Gomisin M2 exhibits anti-cancer and anti-allergic activities and has the potential for Alzheimer’s disease research[1][2].

Product Specifications

CAS Number

[82425-45-4]

Product Name Alternative

(+) -Gomisin M2

UNSPSC

12352005

Target

HIV

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/gomisin-m2.html

Purity

99.75

Solubility

10 mM in DMSO

Smiles

OC1=C(OCO2)C2=CC3=C1C4=C(OC)C(OC)=C(OC)C=C4C[C@H](C)[C@H](C)C3

Molecular Formula

C22H26O6

Molecular Weight

386.44

References & Citations

[1]Min Chen, et al. Rubrisandrins A and B, Lignans and Related anti-HIV Compounds From Schisandra Rubriflora. J Nat Prod. 2006 Dec;69 (12) :1697-701.|[2]Hima Dhakal, et al. Gomisin M2 Inhibits Mast Cell-Mediated Allergic Inflammation via Attenuation of FcεRI-Mediated Lyn and Fyn Activation and Intracellular Calcium Levels. Front Pharmacol. 2019 Aug 2;10:869.