Endothelin-2 (49-69), human (TFA)
Endothelin-2 (49-69), human (TFA) (Endothelin-2 (49-69) (human, canine) (TFA) ) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
Product Specifications
Product Name Alternative
Endothelin-2 (49-69) (human, canine) (TFA) ; Human endothelin-2 (TFA)
UNSPSC
12352209
Target
Endothelin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/endothelin-2-49-69-human-tfa.html
Purity
98.78
Solubility
H2O : 6.67 mg/mL (ultrasonic; adjust pH to 3 with HCl)
Smiles
O=C(N[C@@H](CO)C(N[C@@H](CSSC[C@@H](C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@H]2CC3=CC=CC=C3)=O)=O)=O)NC4=O)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H]4CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CSSC[C@@H](C(N[C@@H](CC7=CNC=N7)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC8=CNC9=CC=CC=C89)C(O)=O)=O)=O)=O)=O)=O)=O)NC2=O)N.O=C(O)C(F)(F)F.[x]
Molecular Formula
C115H160N26O32S4·xC2HF3O2
Molecular Weight
2546.92 (free base)
References & Citations
[1]Grimshaw MJ, et al. Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors. Eur J Immunol. 2002 Sep;32 (9) :2393-400.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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