What is the catalog number for Osthole?

The catalog number for Osthole is HY-N0054.

What sizes are available for Osthole?

Osthole is available in the following size(s): 250 mg, 10 mM - 1 mL, 500 mg, 1 g, 5 g.

How many pack sizes does Osthole come in?

Osthole is available in 5 different pack sizes.

Osthole is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Osthole?

Osthole is manufactured by QuantiMol.

What is the estimated delivery time for Osthole?

Estimated delivery time for Osthole is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Osthole?

The safety data sheet for Osthole is available here: http://file.medchemexpress.com/batch_PDF/HY-N0054/Osthole-SDS-MedChemExpress.pdf.

Osthole

Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells.

Product Specifications

CAS Number

484-12-8

Product Name Alternative

Osthol; NSC 31868

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; HBV; Histamine Receptor; Parasite

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection; Endocrinology; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Osthole.html

Purity

99.94

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C1C=CC2=CC=C(OC)C(C/C=C(C)\C)=C2O1

Molecular Formula

C15H16O3

Molecular Weight

244.29

Precautions

H302, H315, H319, H335

References & Citations

[4]Zhang ZR, et al. Osthole: A Review on Its Bioactivities, Pharmacological Properties, and Potential as Alternative Medicine. Evid Based Complement Alternat Med. 2015;2015:919616.|[1]Kordulewska NK, et al. Changes in gene expression induced by histamine, fexofenadine and osthole: Expression of histamine H1 receptor, COX-2, NF-κB, CCR1, chemokine CCL5/RANTES and interleukin-1β in PBMC allergic and non-allergic patients. Immunobiology.|[2]Tang DZ, et al. Osthole stimulates osteoblast differentiation and bone formation by activation of beta-catenin-BMP signaling. J Bone Miner Res. 2010 Jun;25 (6) :1234-45.|[3]Sun W, et al. Osthole pretreatment alleviates TNBS-induced colitis in mice via both cAMP/PKA-dependent and independent pathways. Acta Pharmacol Sin. 2017 Aug;38 (8) :1120-1128.