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HECW1 Antibody

Product Specifications

Product Name Alternative

E3 ubiquitin-protein ligase HECW1, HECT, C2 and WW domain-containing protein 1, HECT-type E3 ubiquitin transferase HECW1, NEDD4-like E3 ubiquitin-protein ligase 1, hNEDL1

Gene Name

HECW1

Gene ID

23072

UniProt

Q76N89

Antigen Species

Human

Reactivity

Human

Cross Reactivity

Not tested

Immunogen

Recombinant human HECW1

Target

PP-8698

Partner Proteins

E3 ubiquitin-protein ligase HECW1; HECT; C2 and WW domain-containing protein 1; HECT-type E3 ubiquitin transferase HECW1; NEDD4-like E3 ubiquitin-protein ligase 1; hNEDL1

Clone

K40087_8A12

Conjugation

Unconjugated

Applications

Top_IHC

Validation

Top_IHC

Homology

Highest antigen sequence identity to the following orthologs: Mouse - 78%, Pig - 85%, Cynomolgus monkey - 98%

Purity

≥85%

Cores

VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEVLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVKNSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPDDEEISLSTEPESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEEAAVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAPASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPVSELETVIASAC

Storage Temperature

Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower

Identity Mouse

78%

Recombinant Antibody

Not recombinant

IHC Dilution

1:100~1:200

Formulation

Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide

Antibody Type

Monoclonal

Gene Name Synonym

KIAA0322; NEDL1

Target Alternative Name

HECW1

Panel Description

E3 Ligase, Ferroptosis, Ubiquitin-Proteasome System

Host or Source

Mouse

Protein Name

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1

IHC description

Succeed

IP description

Fail (U-251MG)

Shipping Temperature

Shipped at ambient temperature or with ice packs.

Isotype

IgG2a

Available Sizes

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