Caspase-8 Antibody

Product Specifications

Product Name Alternative

Caspase-8, CASP-8, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, FADD-homologous ICE/ced-3-like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, MORT1-associated ced-3 homolog, MACH) [Cleaved into: Caspase-8 subunit p18, Caspase-8 subunit p10]

Gene Name

CASP8

Gene ID

841

UniProt

Q14790

Antigen Species

Human

Reactivity

Human

Cross Reactivity

Not tested

Immunogen

Recombinant human CASP8

Target

P00536PAD

Partner Proteins

Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]

Clone

K29071_4E7

Conjugation

Unconjugated

Applications

Top_IHC

Validation

Top_IHC

Homology

Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 68%, Pig - 63%, Cynomolgus monkey - 89%

Purity

≥85%

Cores

TTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQF

Storage Temperature

Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower

Identity Mouse

68%

Recombinant Antibody

Not recombinant

IHC Dilution

1:100~1:200

Formulation

Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide

Antibody Type

Monoclonal

Gene Name Synonym

MCH5

Target Alternative Name

Caspase-8

Panel Description

Neurodegenerative Diseases Marker

Host or Source

Mouse

Protein Name

Caspase 8

WB Description

Fail (Jurkat (10uM Etoposide Dispose 6h), Jurkat, Jurkat (25uM Etoposide Dispose 6h), Jurkat (50uM Etoposide Dispose 6h), Jurkat (10ng/ml FasL Dispose 4h), Jurkat (10ng/ml FasL Dispose 6h), Jurkat (10ng/ml FasL Dispose 20h) )