ICOSL Recombinant Antibody [HK5.3] (OAAV00453)
Product Specifications
Gene Name
Tumor necrosis factor (ligand) superfamily, member 15
Gene Aliases
BM20K13.3 (tumor necrosis factor (ligand) superfamily, member 15) ; TL; Tl1; Tl1a; TNF ligand-related molecule 1; Tnlg1b; tumor necrosis factor ligand 1b; tumor necrosis factor ligand superfamily member 15; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor; VE; Vegi.
Gene ID
326623
Swiss Prot
P01730
Accession Number
NP_796345.3
Reactivity
Mouse
Immunogen
This antibody was raised by immunising rats with a soluble recombinant TL1A (T77-L252) :Fc protein.
Target
This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG format, for improved compatibility with existing reagents, assays and techniques.
Clonality
Recombinant Monoclonal
Clone
TAN2-2
Type
Recombinant Monoclonal Antibody
Purification
Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Dilution
Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro) . Promotes activation of caspases and apoptosis (By similarity) . Promotes splenocyte alloactivation.
Format
PBS with 0.02% Proclin 300.
Reconstitution
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Fragment
IgG, kappa
Specificity
This antibody is specific for TL1A, a member of the TNF ligand family. TL1A is expressed by endothelial cells, tissue macrophages, monocyte-derived dendritic cells, plasma cells and lamina propria-derived lymphocytes. Among peripheral blood cells, TL1A has been shown to be expressed predominantly by CD4+CCR9+ lymphocytes. Its expression has been shown to be induced by TNF alpha, IL-1 alpha and IFN gamma.
NCBI Gene Symbol
Tnfsf15
Host or Source
Rabbit
Protein Name
Tumor necrosis factor ligand superfamily member 15
Gene Name URL
Tnfsf15
Nucleotide Accession Number
NM_177371.3
Curated Selection
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