CD81 Recombinant Antibody [1D6] (OAAV00394)

Product Specifications

Gene Name

Fc fragment of IgG receptor Ia

Gene Aliases

CD64; CD64A; Fc fragment of IgG, high affinity Ia, receptor (CD64) ; Fc fragment of IgG, high affinity Ia, receptor for (CD64) ; Fc gamma receptor Ia; Fc-gamma receptor I A1; Fc-gamma RI; fc-gamma RIA; FcgammaRI; fcgammaRIa; FCRI; high affinity immunoglobulin gamma Fc receptor I; IGFR1; IgG Fc receptor I.

Gene ID

2209

Swiss Prot

P01374

Accession Number

NP_000557.1ÃƒÂ¯Ã‚Â»Ã‚Â¿

Reactivity

Human

Immunogen

This recombinant antibody was prepared by cloning the single chain fragment (scFv) derived from the murine anti-human CD64 mAb m22 into the bacterial expression vector pBM1.1, and fusing it to a deletion mutant of Pseudomonas exotoxin A (ETA') .

Target

This chimeric rabbit antibody was made using the variable domain sequences of the original IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Clonality

Recombinant Monoclonal

Clone

H22

Type

Recombinant Monoclonal Antibody

Purification

Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.

Format

PBS with 0.02% Proclin 300.

Reconstitution

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Fragment

IgG, kappa

Specificity

This immunotoxin is specific for human CD64, and specifically an epitope outside the Fc binding domain. The binding activity of the VH/VL antibody format was unaffected by fusion of the m22 (scFv) coding regions to the truncated ETA coding sequences