GPIIb/IIIa Recombinant Antibody [10E5] (OAAV00338)

Product Specifications

Gene Name

Selectin, lymphocyte

Gene Aliases

AI528707; CD62; CD62 antigen-like family member L; CD62L; L; LAM-1; LECAM; LECAM1; LECAM-1; leukocyte adhesion molecule 1; leukocyte-endothelial cell adhesion molecule 1; Lnhr; L-sel; L-selectin; Ly-2; Ly-22; Lya; Lyam; Lyam1; Lyam-1; Ly-m2; Ly-m22; lymph node homing receptor; lymphocyte antigen 22; lymphocyte surface MEL-14 antigen.

Gene ID

20343

Swiss Prot

P02751

Accession Number

NP_035476.1ÃƒÂ¯Ã‚Â»Ã‚Â¿

Reactivity

Mouse

Immunogen

C3H/eb mouse B lymphoma 38C-13.

Target

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Clonality

Recombinant Monoclonal

Clone

MEL-14

Type

Recombinant Monoclonal Antibody

Purification

Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes (PubMed:1693096) . Promotes initial tethering and rolling of leukocytes in endothelia (By similarity) .

Format

PBS with 0.02% Proclin 300.

Reconstitution

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Fragment

IgG, kappa

Specificity

This antibody binds to mouse CD62L the mouse peripheral lymph node homing receptor, which is a lectin-like cell surface protein rapidly down-regulated upon cell activation with phorbol 12-myristate 13-acetate.