What is the catalog number for CGP52432?

The catalog number for CGP52432 is HY-103531.

What sizes are available for CGP52432?

CGP52432 is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does CGP52432 come in?

CGP52432 is available in 6 different pack sizes.

Is CGP52432 in stock?

CGP52432 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CGP52432?

CGP52432 is manufactured by QuantiMol.

What is the estimated delivery time for CGP52432?

Estimated delivery time for CGP52432 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CGP52432?

The safety data sheet for CGP52432 is available here: http://file.medchemexpress.com/batch_PDF/HY-103531/CGP52432-SDS-MedChemExpress.pdf.

CGP52432

CGP52432 is a GABAB receptor antagonist, with an IC50 of 85 nM.

Product Specifications

CAS Number

139667-74-6

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/CGP52432.html

Purity

98.57

Solubility

DMSO : 5 mg/mL (ultrasonic; warming) |H2O : 4 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=P(C(OCC)OCC)(CCCNCC1=CC=C(Cl)C(Cl)=C1)O

Molecular Formula

C15H24Cl2NO4P

Molecular Weight

384.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Lanza M, et al. CGP 52432: a novel potent and selective GABAB autoreceptor antagonist in rat cerebral cortex. Eur J Pharmacol. 1993 Jun 24;237 (2-3) :191-5.|[2]Sweeney FF, et al. Activation but not blockade of GABAB receptors during early-life alters anxiety in adulthood in BALB/c mice. Neuropharmacology. 2014 Jun;81:303-10.|[3]Kobuchi S, et al. Mechanisms underlying the renoprotective effect of GABA against ischaemia/reperfusion-induced renal injury in rats. Clin Exp Pharmacol Physiol. 2015 Mar;42 (3) :278-86.