GITR Recombinant Antibody [YGITR 860.103.5] (OAAV00279)
Product Specifications
Gene Name
Cholinergic receptor nicotinic alpha 1 subunit
Gene Aliases
Acetylcholine receptor subunit alpha; acetylcholine receptor, nicotinic, alpha 1 (muscle) ; ACHRA; ACHRD; cholinergic receptor, nicotinic alpha 1; cholinergic receptor, nicotinic, alpha 1 (muscle) ; cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) ; CHRNA; CMS1A; CMS1B; CMS2A; FCCMS; muscle nicotinic acetylcholine receptor; nicotinic acetylcholine receptor alpha subunit; nicotinic cholinergic receptor alpha 1; SCCMS.
Gene ID
1134
Swiss Prot
P00533
Accession Number
NP_000070.1
Immunogen
Human muscle AChR.
Clonality
Recombinant Monoclonal
Clone
MAb 192
Type
Recombinant Monoclonal Antibody
Purification
Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Dilution
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Format
PBS with 0.02% Proclin 300.
Reconstitution
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Fragment
IgG2b, kappa
Specificity
The antibody binds to human muscle AChR with a Kd of 10 pM, to mouse muscle AChR with a Kd of 50 pM, and to rat muscle AChR with a Kd of 646 nM.
NCBI Gene Symbol
CHRNA1
Host or Source
Rat
Protein Name
Acetylcholine receptor subunit alpha
Gene Name URL
CHRNA1
Nucleotide Accession Number
NM_000079.3
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