VAP-1 Recombinant Antibody [TK8-14] (OAAV00164)

Product Specifications

Gene Name

Amine oxidase copper containing 3

Gene Aliases

Amine oxidase, copper containing 3 (vascular adhesion protein 1) ; copper amine oxidase; HPAO; membrane primary amine oxidase; placenta copper monamine oxidase; semicarbazide-sensitive amine oxidase; SSAO; VAP1; VAP-1; Vascular adhesion protein 1.

Gene ID

8639

Swiss Prot

P07766

Accession Number

NP_001264660.1ÃƒÂ¯Ã‚Â»Ã‚Â¿

Reactivity

Human

Immunogen

Affinity purified VAP-1 from tonsil stroma of human origin.

Target

This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Clonality

Recombinant Monoclonal

Clone

2D10

Type

Recombinant Monoclonal Antibody

Purification

Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

Cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has semicarbazide-sensitive (SSAO) monoamine oxidase activity. May play a role in adipogenesis.

Format

PBS with 0.02% Proclin 300.

Reconstitution

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Fragment

IgG, kappa

Specificity

Recognises human Vascular Adhesion Protein-1 (VAP-1), a glycosylated homodimeric membrane protein consisting of two 90 kDa subunits connected by disulfide bonds. 2D10 is a conformational specific antibody which recognizes an epitope present only in the dimeric form of VAP-1. Elevated soluble VAP-1 serum- levels have been described in several inflammatory- diseases as well as colorectal cancer.