CD40 Recombinant Antibody [G28.5] (OAAV00095)
Product Specifications
Gene Name
CD40 molecule
Gene Aliases
B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDW40; p50; TNFRSF5; tumor necrosis factor receptor superfamily member 5.
Gene ID
958
Swiss Prot
P25942
Accession Number
NP_001241.1
Reactivity
Human
Immunogen
Human erythrocyte-rosette-negative tonsillar lymphocytes.
Target
This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Clonality
Recombinant Monoclonal
Clone
G28.5
Type
Recombinant Monoclonal Antibody
Purification
Purified
Dilution
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Format
PBS with 0.02% Proclin 300.
Reconstitution
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Fragment
IgG, kappa
Specificity
48 kD Type I glycoprotein, a member of the TNFR superfamily primarily expressed on normal or malignant B cells or B cell lines, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells.
NCBI Gene Symbol
CD40
Host or Source
Rabbit
Protein Name
Tumor necrosis factor receptor superfamily member 5
Gene Name URL
CD40
Nucleotide Accession Number
NM_001250.5
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