CD34 Recombinant Antibody [My10] (OAAV00091)

Product Specifications

Gene Name

CD34 molecule

Gene Aliases

CD34 antigen; hematopoietic progenitor cell antigen CD34.

Gene ID

947

Swiss Prot

P28906

Accession Number

NP_001020280.1ÃƒÂ¯Ã‚Â»Ã‚Â¿

Reactivity

Human

Immunogen

KG-1a Human myeloblastic leukemic cell line (immature human myeloid cell line) from a patient with nonlymphocytic leukemia.

Target

This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Clonality

Recombinant Monoclonal

Clone

My10

Type

Recombinant Monoclonal Antibody

Purification

Purified

Dilution

Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.

Format

PBS with 0.02% Proclin 300.

Reconstitution

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Fragment

IgG, kappa

Specificity

Human CD34, an ~105 - 120 kDa type 1 transmembrane glycoprotein expressed on the surface of most human hematopoietic stem and progenitor cells (HSPCs) as well as on mesenchymal stem cells, embryonic fibroblasts, endothelial cells, neurons, and some tumor cell lines.