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SDH-IN-18

SDH-IN-18 (Compound 3a) is an inhibitor for succinate dehydrogenase (SDH) with an IC50 of 8.70 mg/L. SDH-IN-18 destroys fungal morphology and reproduction, exhibits antifungal activity against Rhizoctonia solani and Sclerotinia sclerotiorum with EC50 of 0.48 and 1.4 mg/L[1].

Product Specifications

CAS Number

723748-50-3

UNSPSC

12352005

Target

Fungal; Succinate Dehydrogenase

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sdh-in-18.html

Smiles

O=C(NC1=CC=CC=C1C2=CC=C([Si](C)(C)C)C=C2)C3=C(Cl)N=CC=C3

Molecular Formula

C21H21ClN2OSi

Molecular Weight

380.94

References & Citations

[1]Quan X, et al., Design, Synthesis, and Biological Activity of Silicon-Containing Carboxamide Fungicides. J Agric Food Chem. 2024 Aug 7;72 (31) :17260-17270.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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