SDH-IN-18
SDH-IN-18 (Compound 3a) is an inhibitor for succinate dehydrogenase (SDH) with an IC50 of 8.70 mg/L. SDH-IN-18 destroys fungal morphology and reproduction, exhibits antifungal activity against Rhizoctonia solani and Sclerotinia sclerotiorum with EC50 of 0.48 and 1.4 mg/L[1].
Product Specifications
CAS Number
723748-50-3
UNSPSC
12352005
Target
Fungal; Succinate Dehydrogenase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sdh-in-18.html
Smiles
O=C(NC1=CC=CC=C1C2=CC=C([Si](C)(C)C)C=C2)C3=C(Cl)N=CC=C3
Molecular Formula
C21H21ClN2OSi
Molecular Weight
380.94
References & Citations
[1]Quan X, et al., Design, Synthesis, and Biological Activity of Silicon-Containing Carboxamide Fungicides. J Agric Food Chem. 2024 Aug 7;72 (31) :17260-17270.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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