FTO Recombinant Antibody [8M13] (ATM00001)
Product Specifications
Gene Name
Alpha-ketoglutarate-dependent dioxygenase
Gene Aliases
FTO
Gene ID
79068
Swiss Prot
Q9C0B1-1
Reactivity
Human
Immunogen
Recombinant Human FTO aa328-505_x005F
Clonality
Recombinant Monoclonal
Clone
8M13
Type
Recombinant Monoclonal Antibody
Applications
IF, WB_x005F
Purification
Protein A
Concentration
1 mg/mL
Dilution
RNA demethylase that mediates oxidative demethylation of different RNA species, such as mRNAs, tRNAs and snRNAs, and acts as a regulator of fat mass, adipogenesis and energy homeostasis (PubMed:22002720, PubMed:26458103, PubMed:28002401, PubMed:30197295, PubMed:26457839, PubMed:25452335) . Specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:22002720, PubMed:26458103, PubMed:30197295, PubMed:26457839, PubMed:25452335), among other targets. _x005F
Format
PBS w/ 0.09% sodium azide
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles._x005F
Molecular Weight
58.3 kDa
Fragment
IgG
Protein Length
505
NCBI Gene Symbol
FTO
Host or Source
Rabbit
Protein Name
Alpha-ketoglutarate-dependent dioxygenase FTO
Gene Name URL
FTO_x005F
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