Amyloid Beta Peptide 1-40 + C-term Cysteine Monomers

Amyloid Beta 1-40 peptide (Aβ40) is a major isoform implicated in Alzheimer’s disease, contributing to plaque formation and neurotoxicity despite being less aggregation-prone than Aβ42. Aβ40’s interaction with neural membranes and metal ions accelerates oligomerization and oxidative stress, disrupting neuronal function. Genetic factors like PLXNB1 influence glial responses and plaque morphology, modulating neuroinflammation and disease progression. StressMarq’s Amyloid Beta 1-40 + C-Term Cysteine Monomers are produced synthetically and present as a monomeric band at the expected molecular weight (MW) on SDS-PAGE via Coomassie Stain and Western Blot. This construct has a C-terminal cysteine to facilitate maleimide conjugations by the end-user for downstream applications where a label is desired.

Aβ 1-40-Cys, AB40-C, Amyloid beta 1-40-C, Beta-amyloid peptide (1-40) with cysteine, APP40-Cys, BAPP40-Cys, Modified Aβ40, Amyloid-beta (A4) precursor protein, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide (CVAP), Protease nexin-II (PN-II)

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