Dasabuvir (Standard)

Dasabuvir (Standard) is the analytical standard of Dasabuvir. This product is intended for research and analytical applications. Dasabuvir (ABT-333) is a nonnucleoside hepatitis C virus (HCV) polymerase inhibitor. Dasabuvir inhibits RNA-dependent RNA polymerase encoded by the HCV NS5B gene. Dasabuvir inhibits genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC50 values of 7.7 and 1.8 nM, respectively[1].

Product Specifications

CAS Number

[1132935-63-7]

Product Name Alternative

ABT-333 (Standard)

UNSPSC

12352005

Target

DNA/RNA Synthesis; HCV; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dasabuvir-standard.html

Smiles

CS(=O)(NC1=CC=C2C=C(C3=CC(N(C(N4)=O)C=CC4=O)=CC(C(C)(C)C)=C3OC)C=CC2=C1)=O

Molecular Formula

C26H27N3O5S

Molecular Weight

493.57

References & Citations

[1]Kati W, et al. In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor. Antimicrob Agents Chemother. 2015 Mar;59 (3) :1505-11.