Tasosartan

Tasosartan is a long-acting angiotensin II (AngII) receptor antagonist.

Product Specifications

CAS Number

[145733-36-4]

Product Name Alternative

WAY-ANA 756

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Tasosartan.html

Concentration

10mM

Purity

99.32

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1CCC2=C(C)N=C(C)N=C2N1CC3=CC=C(C4=CC=CC=C4C5=NNN=N5)C=C3

Molecular Formula

C23H21N7O

Molecular Weight

411.46

Precautions

H302, H315, H319, H335

References & Citations

[1]Maillard MP, et al. Tasosartan, enoltasosartan, and angiotensin II receptor blockade: the confounding role of protein binding. J Pharmacol Exp Ther. 2000 Nov;295 (2) :649-54.|[2]Elokdah HM, et al. Novel human metabolites of the angiotensin-II antagonist Tasosartan and their pharmacological effects. Bioorg Med Chem Lett. 2002 Aug 5;12 (15) :1967-71.