Calcifediol-d3

Calcifediol-d3 is a deuterium labeled Calcifediol. Calcifediol, is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels[1][2][3].

Product Specifications

CAS Number

[140710-94-7]

Product Name Alternative

25-Hydroxy Vitamin D3-d3

UNSPSC

12352211

Hazard Statement

H301+H311, H330, H372

Target

Endogenous Metabolite; Isotope-Labeled Compounds; VD/VDR

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Metabolic Disease

Purity

98.96

Solubility

DMSO : 100mg/mL (ultrasonic)

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)(O)C)([H])/C(CCC1)=C/C([2H])=C3\C(CC[C@@H](C3)O)=C([2H])/[2H]

Molecular Formula

C27H41D3O2

Molecular Weight

403.66

Precautions

H301+H311, H330, H372

References & Citations

[1]Castoldi A, et al. Calcifediol-loaded liposomes for local treatment of pulmonary bacterial infections. Eur J Pharm Biopharm. 2016 Nov 22.|[2]Wei Zheng, et al. Vitamin D-induced vitamin D receptor expression induces tamoxifen sensitivity in MCF-7 stem cells via suppression of Wnt/β-catenin signaling. Biosci Rep. 2018 Dec 7;38 (6) :BSR20180595.