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Aristoquinoline

Aristoquinoline (Compound 1) is an alkaloid can be isolated from Aristotelia chilensis. Aristoquinoline has α3β4 nAChR inhibitory activity[1].

Product Specifications

CAS Number

[2720562-34-3]

UNSPSC

12352005

Target

NAChR

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aristoquinoline.html

Solubility

10 mM in DMSO

Smiles

CC([C@H]1C[C@@H]2C(C)=CC1)(C)N[C@H]2C3=CC=NC4=C3C=CC=C4

Molecular Formula

C20H24N2

Molecular Weight

292.42

References & Citations

[1]Rusali LE, et al. Synthesis of α3β4 Nicotinic Acetylcholine Receptor Modulators Derived from Aristoquinoline That Reduce Reinstatement of Cocaine-Seeking Behavior. J Med Chem. 2024 Jan 11;67 (1) :529-542.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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