Aristoquinoline
Aristoquinoline (Compound 1) is an alkaloid can be isolated from Aristotelia chilensis. Aristoquinoline has α3β4 nAChR inhibitory activity[1].
Product Specifications
CAS Number
[2720562-34-3]
UNSPSC
12352005
Target
NAChR
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aristoquinoline.html
Solubility
10 mM in DMSO
Smiles
CC([C@H]1C[C@@H]2C(C)=CC1)(C)N[C@H]2C3=CC=NC4=C3C=CC=C4
Molecular Formula
C20H24N2
Molecular Weight
292.42
References & Citations
[1]Rusali LE, et al. Synthesis of α3β4 Nicotinic Acetylcholine Receptor Modulators Derived from Aristoquinoline That Reduce Reinstatement of Cocaine-Seeking Behavior. J Med Chem. 2024 Jan 11;67 (1) :529-542.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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