B7-2/CD86, Human (HEK293, Fc)
Product Specifications
UNSPSC Description
B7-2/CD86 Protein, Human (HEK293, Fc) is a polypeptide chain with the C-termimal human IgG1 Fc fragment produced in HEK293 cells. B7-2 (CD86) is a costimulatory molecule expressed by antigen-presenting cells (APCs), which interacts with CD28 for T-cell activation and survival and with CTLA4 for immune regulation.
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/b7-2-cd86-protein-human-hek293-fc.html
Purity
97.00
Smiles
LSGAAPLKIQ AYFNETADLP CQFANSQNQS LSELVVFWQD QENLVLNEVY LGKEKFDSVH SKYMGRTSFD SDSWTLRLHN LQIKDKGLYQ CIIHHKKPTG MIRIHQMNSE LSVLANFSQP EIVPISNITE NVYINLTCSS IHGYPEPKKM SVLLRTKNST IEYDGVMQKS QDNVTELYDV SISLSVSFPD VTSNMTIFCI LETDKTRLLS SPFSIELEDP QPPPDHIP
Molecular Weight
65-80 kDa
References & Citations
[1]Han L, et al. A monoclonal antibody against CD86 and its protection in a murine lupus nephritis model of chronic graft-versus-host disease. Immunopharmacol Immunotoxicol. 2017 Oct;39(5):285-291.
Shipping Conditions
Blue Ice
Storage Conditions
Stored at -20°C for 2 years
Available Sizes
Curated Selection
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