PrP (106-126)
PrP (106-126) is a peptide corresponding to the prion protein (PrP) amyloidogenic region, and its biochemical properties resemble the infectious form of prion protein.
Product Specifications
CAS Number
148439-49-0
Product Name Alternative
Prion protein (106-126)
UNSPSC
12352209
Target
Prion Protein
Type
Peptides
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/PrP_106-126.html
Purity
99.59
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic; warming)
Smiles
O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CCSC)C(N[C@@H](CCCCN)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CCSC)C(N[C@@H](C)C(NCC(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(NCC(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(NCC(NCC(N[C@@H](CC(C)C)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N
Molecular Formula
C80H138N26O24S2
Molecular Weight
1912.30
References & Citations
[1]Yang W, et al. PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling. CNS Neurosci Ther. 2017 May;23 (5) :416-427.|[2]Cooper I, et al. Interactions of the prion peptide (PrP 106-126) with brain capillary endothelial cells: coordinated cell killing and remodeling of intercellular junctions. J Neurochem. 2011 Feb;116 (4) :467-75.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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