Anti-XAB2 Antibody

Rabbit Polyclonal Antibody specific to XAB2

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Protein HCNP, XPA-binding protein 2

Gene Name

XAB2

NCBI Gene ID

UniProt

Q9HCS7

Cellular Locus

Nucleus

Host

Rabbit

Reactivity

Human

Immunogen

Peptide corresponding to aa 840-855 of human XAB2 protein.

Target Antigen

Pre-mRNA-splicing factor SYF1

Target

XAB2

Clonality

Polyclonal

Type

Antibody

Applications

Field of Research

Cancer research

Purification Method

Purified by immunoaffinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium which is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28076346). Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing (PubMed:10944529, PubMed:17981804). {PubMed:10944529, PubMed:11991638, PubMed:17981804, PubMed:28076346, PubMed:28502770}.

Additionnal Information

Immunoblotting: use at 1:500-1:1,000 dilution. A band of approximately 100 kD (the monomeric form) is detected.

Storage Conditions

This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze- thaw cycles.

Specificity

This antibody recognizes human XAB2 protein (XPA-binding protein 2) which appears to be involved in transcription- coupled DNA repair and transcription. XAB2 binds to XPA, a key factor in nucleotide excision repair pathways.