RO7196472
RO7196472 is a potent and selective macrocyclic peptide antibiotic that targets Acinetobacter strains. RO7196472 inhibits Acinetobacter strain activity by specifically binding to the Lipopolysaccharide (LPS) binding site on the LptB2FG complex located on the inner membrane of Acinetobacter strains, thereby blocking LPS transport and suppressing Acinetobacter strain activity[1].
Product Specifications
CAS Number
[2097285-98-6]
UNSPSC
12352209
Target
Antibiotic
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ro7196472.html
Smiles
ClC1=C2C(CNC([C@@H](N(C([C@@H](NC([C@@H](NCC3=CC=CN=C3S2)CCCN)=O)CCCCN)=O)C)CC4=CNC5=CC=CC=C45)=O)=C(C6=CN=C(N)C=C6)C=C1
Molecular Formula
C41H49ClN10O3S
Molecular Weight
797.41
References & Citations
[1]Pahil KS, et al. A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature. 2024 Jan;625 (7995) :572-577.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
CBX5 (Chromobox Protein Homolog 5, Antigen p25, Heterochromatin Protein 1 Homolog alpha, HP1 alpha, HP1alpha, HP1A)
CBX5 (Chromobox Protein Homolog 5, Antigen p25, Heterochromatin Protein 1 Homolog alpha, HP1 alpha, HP1alpha, HP1A)