Anti-DLL3 Antibody (anti-DLL3 arm derived from AMG-757)
Selected Variant
HY-P990104-01
Size: 1 mg
Anti-DLL3 Antibody (anti-DLL3 arm derived from AMG-757) is the anti-DLL3 arm of the bispecific T-cell engager (BiTE) antibody-Tarlatamab (AMG-757). Tarlatamab targets both DLL3 and CD3.
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352203
Target
Notch
Type
Inhibitory Antibodies
Related Pathways
Neuronal Signaling; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-dll3-antibody-anti-dll3-arm-derived-from-amg-757.html
Purity
99.39
Solubility
10 mM in DMSO
Smiles
[Anti-DLL3Antibody(anti-DLL3armderivedfromAMG-757)]
Molecular Weight
(145.18 kDa)
References & Citations
[1]Giffin MJ, et al. AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer. Clin Cancer Res. 2021 Mar 1;27 (5) :1526-1537.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
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