Miriplatin

Product Specifications

UNSPSC Description

Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents.

Target Antigen

DNA Alkylator/Crosslinker

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Miriplatin.html

Solubility

Acetone : < 1 mg/mL (ultrasonic)|DMF : < 1 mg/mL|H2O : < 0.1 mg/mL

Smiles

NC1CCCCC1N.[O-]C(CCCCCCCCCCCCC)=O.[O-]C(CCCCCCCCCCCCC)=O.[Pt+2]

Molecular Weight

764.00

References & Citations

[1]Kishimoto S, et al. Antitumor effects of a novel lipophilic platinum complex (SM-11355) against a slowly-growing rat hepatic tumor after intra-hepatic arterial administration. Biol Pharm Bull. 2000 Mar;23(3):344-8.|[2]Hanada M, et al. Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of tumors implanted in rat livers by inducing platinum-DNA adducts to form and massive apoptosis. Cancer Chemother Pharmacol. 2009 Aug;64(3):473-83.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-16325A/Miriplatin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-16325A/Miriplatin-SDS-MedChemExpress.pdf

Clinical Information

Launched

CAS Number

141977-79-9

Available Sizes

Curated Selection

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