Miriplatin
Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents.
Product Specifications
CAS Number
141977-79-9
Product Name Alternative
SM-11355
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Miriplatin.html
Purity
98.0
Solubility
Acetone : < 1 mg/mL (ultrasonic)|DMF : < 1 mg/mL|H2O : < 0.1 mg/mL
Smiles
NC1CCCCC1N.[O-]C(CCCCCCCCCCCCC)=O.[O-]C(CCCCCCCCCCCCC)=O.[Pt+2]
Molecular Formula
C34H68N2O4Pt
Molecular Weight
764.00
Precautions
H302, H315, H319, H335
References & Citations
[1]Kishimoto S, et al. Antitumor effects of a novel lipophilic platinum complex (SM-11355) against a slowly-growing rat hepatic tumor after intra-hepatic arterial administration. Biol Pharm Bull. 2000 Mar;23 (3) :344-8.|[2]Hanada M, et al. Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of tumors implanted in rat livers by inducing platinum-DNA adducts to form and massive apoptosis. Cancer Chemother Pharmacol. 2009 Aug;64 (3) :473-83.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
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