Maleic acid
Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes.
Product Specifications
CAS Number
[110-16-7]
UNSPSC
12352211
Hazard Statement
H302+H312, H315, H317, H318, H335
Target
Bacterial; Endogenous Metabolite
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Maleic_Acid.html
Purity
99.98
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(O)/C=C\C(O)=O
Molecular Formula
C4H4O4
Molecular Weight
116.07
Precautions
H302+H312, H315, H317, H318, H335
References & Citations
[1]Fonda ML, et al. Glutamate decarboxylase. Substrate specificity and inhibition by carboxylic acids. Biochemistry. 1972 Mar 28;11 (7) :1304-9.|[2]Paudyal R, et al. A novel approach in acidic disinfection through inhibition of acid resistance mechanisms; Maleic acid-mediated inhibition of glutamate decarboxylase activity enhances acid sensitivity of Listeria monocytogenes. Food Microbiol. 2018 Feb;69:96-104.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Curated Selection
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