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H3K4 (Me3) (1-20)

H3K4 (Me3) (1-20) is a histone peptide. Trimethylation of histone H3 on lysine 4 (H3K4 me3) is found in active euchromatin but not in silent heterochromatin[1][2].

Product Specifications

UNSPSC

12352209

Target

Histone Demethylase

Type

Peptides

Related Pathways

Epigenetics

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/h3k4-me3-1-20.html

Purity

98.69

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCC[N+](C)(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(NCC(NCC(N[C@@H](CCCCN)C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C94H174N35O27

Molecular Weight

2226.64

References & Citations

[1]Mulder KW, et al. Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complex. Nucleic Acids Res. 2007;35 (7) :2428-2439.|[2]Fujino T, et al. Alteration of histone H3K4 methylation in glomerular podocytes associated with proteinuria in patients with membranous nephropathy. BMC Nephrol. 2016;17 (1) :179. Published 2016 Nov 17.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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