(2E) -Hexenoyl-CoA

(2E) -Hexenoyl-CoA (Hex-2-trans-enoyl-CoA) is an intermediate in fatty acid metabolism. (2E) -Hexenoyl-CoA is the substrate of the enzymes enoyl-coenzyme A reductase, acyl-CoA oxidase, acyl-CoA dehydrogenase, long-chain-acyl-CoA dehydrogenase and Oxidoreductases[1].

Product Specifications

CAS Number

[10018-93-6]

Product Name Alternative

Hex-2-trans-enoyl-CoA

UNSPSC

12352204

Target

Endogenous Metabolite

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2e-hexenoyl-coa.html

Solubility

10 mM in DMSO

Smiles

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](OP(O)(O)=O)[C@@H](COP(O)(OP(O)(OCC(C)([C@H](C(NCCC(NCCSC(/C=C/CCC)=O)=O)=O)O)C)=O)=O)O3

Molecular Formula

C27H44N7O17P3S

Molecular Weight

863.66

References & Citations

[1]Takeshi Miyazawa, et al. Identification of Middle Chain Fatty Acyl-CoA Ligase Responsible for the Biosynthesis of 2-Alkylmalonyl-CoAs for Polyketide Extender Unit. J Biol Chem. 2015 Nov 6;290 (45) :26994-27011.