Recombinant Protein L
Protein L is a multi-domain protein found on the surface of Peptostreptococcus magnus, also known as Peptostreptococcus magnus Protein L (PPL) . Unlike Protein A or Protein G, Protein L primarily binds to the kappa light chain of antibodies without interfering with the antigen-binding domain. This unique binding mechanism enables Protein L to interact with a broader range of antibody classes and subtypes, including human IgG, IgM, IgA, and IgD containing kappa light chains, as well as mouse IgG, IgM, rat IgG, Fab fragments, and single-chain variable fragments (scFv), among others.
Product Specifications
Product Name Alternative
Protein L, Peptostreptococcus magnus Protein L, PPL
Expression System
E. coli
Nature
Recombinant
Applications
Detection and purification of antibodies and antibody fragments (Fab, ScFv) that contain kappa light chains but not the Fc region.
Stability
Endotoxin
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Form
Lyophilized
Buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping Conditions
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Notes
For research use only.
Species
Peptostreptococcus magnus
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