Propargyl-PEG1-SS-PEG1-acid
Product Specifications
UNSPSC Description
Propargyl-PEG1-SS-PEG1-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-PEG1-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/propargyl-peg1-ss-peg1-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCOCCSSCCOCC#C
Molecular Weight
264.36
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140109/Propargyl-PEG1-SS-PEG1-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140109/Propargyl-PEG1-SS-PEG1-acid-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1807503-85-0
Available Sizes
Curated Selection
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