Acelarin
Acelarin (NUC-1031) is a ProTide transformation and enhancement of the widely-used nucleoside analogue, gemcitabine.
Product Specifications
CAS Number
840506-29-8
Product Name Alternative
NUC-1031
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Acelarin.html
Purity
99.13
Solubility
DMSO : ≥ 36 mg/mL
Smiles
O=C1N=C(N)C=CN1[C@@H]2O[C@H](COP(OC3=CC=CC=C3)(N[C@H](C(OCC4=CC=CC=C4)=O)C)=O)[C@@H](O)C2(F)F
Molecular Formula
C25H27F2N4O8P
Molecular Weight
580.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Slusarczyk M, et al. Application of ProTide technology to gemcitabine: a successful approach to overcome the key cancer resistance mechanisms leads to a new agent (NUC-1031) in clinical development. J Med Chem. 2014 Feb 27;57 (4) :1531-42.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Mouse Monoclonal CLCN3 Antibody (S258-5) [Janelia Fluor 549]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NBP2-59379JF549 0.1 mL
Mouse Monoclonal CLCN3 Antibody (S258-5) [Janelia Fluor 549]
Sign In for Pricing
View Details 
