Fz7-21S
Fz7-21S is a negative control of Fz7-21. Fz7-21 is a potent peptide antagonist of FZD7 receptors[1].
Product Specifications
CAS Number
[2247635-24-9]
UNSPSC
12352209
Target
Wnt
Type
Peptides
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fz7-21s.html
Purity
98.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H]1N(CCC1)C([C@@H](NC(C)=O)CC(C)C)=O)N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CCSC)C(N[C@H](C(N)=O)CC3=CC=C(C=C3)O)=O)=O)=O)CC4=CN=CN4)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O
Molecular Formula
C83H114N18O24S
Molecular Weight
1779.96
References & Citations
[1]Aaron H Nile, et al. A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat Chem Biol. 2018 Jun;14 (6) :582-590.|[2]Nile AH, et, al. A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat Chem Biol. 2018 Jun;14 (6) :582-590.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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