Cephalotaxine
Cephalotaxlen ((-) -Cephalotaxine) is an alkaloid that can be isolated from Cephalotaxus fortunei, with antileukemic and antiviral activities. Cephalotaxlen has anti-ZIKV (Zika virus) activity[1][2][3].
Product Specifications
CAS Number
24316-19-6
Product Name Alternative
(-) -Cephalotaxine; ZINC19795976
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Flavivirus
Type
Natural Products
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/cephalotaxlen.html
Purity
99.21
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@](C(C=C(OCO2)C2=C3)=C3CCN4CCC5)([H])[C@]45C=C1OC
Molecular Formula
C18H21NO4
Molecular Weight
315.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Wang DZ, et al. Studies on the alkaloids of Cephalotaxus. IX. Semi-synthesis of cephalotaxine esters and their anti-leukemic activity Yao Xue Xue Bao. 1992;27 (3) :178-84.|[2]Efferth T, et al. Molecular modes of action of cephalotaxine and homoharringtonine from the coniferous tree Cephalotaxus hainanensis in human tumor cell lines. Naunyn Schmiedebergs Arch Pharmacol. 2003 Jan;367 (1) :56-67.|[3]Zheng-Zong Lai, et al. Cephalotaxine inhibits Zika infection by impeding viral replication and stability. Biochem Biophys Res Commun. 2020 Feb 19; 522 (4) : 1052–1058.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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